This EMCREG-International Newsletter describe historical and physical examination findings crucial for the evaluation of end organ damage. Also provided are descriptions of hypertension associated with the following disease processes: Asymptomatic Hypertension, Acute Coronary Syndrome, Acute Heart Failure Syndromes, Neurological Emergencies, Cocaine or Amphetamine Induced Hypertension, and Aortic Dissection are provided with treatment recommendations. Through collaboration with colleagues from a variety of specialties, patients with hypertension can receive optimal therapy when presenting to any acute care setting.